AESTURA Atobarrier 365 Hydro Cera-HA — Ampoule Réparatrice Barrière

This ampoule contains a blend of active ingredients designed to rebuild the lipid architecture of the skin barrier while providing measurable hydration for several days.

Niacinamide (Vitamin B3): stimulates the endogenous synthesis of ceramides and free fatty acids in keratinocytes. Reduces transepidermal water loss (TEWL) and helps even out the complexion of fragile epidermis.

Cera-Hyaluronic Acid™ : AMOREPACIFIC's patented technology combining 1001 ppm of hyaluronic acid with two types of ceramides — 210 ppm of Hydroxypropyl Bispalmitamide MEA (biomimetic pseudo-ceramide) and 0.75 ppm of Ceramide NP. This synergy allows moisture retention twice as high as hyaluronic acid alone..

Cholesterol (Cholesterol): a lipid identical to the one that makes up 25% of the stratum corneum. Combined with ceramides and fatty acids, it forms a lamellar structure that mimics the natural intercellular cement.

3-O-Ethyl Ascorbic Acid : a stable, water-soluble vitamin C derivative, active against oxidation and capable of brightening pigmentation spots without sensitizing the skin.

Adenosine : a molecule recognized by the Korean MFDS for its anti-aging properties: stimulates collagen production and improves dermal microcirculation.

☀️ Morning routine

1. After cleansing and toner, place 2-3 drops in the palm of your hand.
2. Warm it for a few seconds between your hands, then gently pat onto your face and neck.
3. Let it absorb for 30 seconds before applying your moisturizer — the ampoule prepares the skin so the following active ingredients penetrate better.
4. Finish with your sunscreen (adenosine and vitamin C make this step non-negotiable).

🌙 Evening routine

1. After double cleansing and toner, apply the ampoule in the same way.
2. If your skin is particularly dehydrated, you can layer a second coat on tension areas (cheekbones, temples).
3. Seal with Atobarrier 365 cream for a duo effect: the cream’s ceramide capsules extend the ampoule’s action.

Lightly viscous fluid texture, fast absorption without a greasy film — perfect before makeup.

This bulb is intended for specific profiles, where the skin barrier shows signs of structural weakness:

• Chronically dehydrated skin : those that absorb everything given to them without ever appearing plumped. Hyaluronic acid combined with ceramides retains water in the upper layers of the epidermis.
• Reactive sensitive skin : diffuse redness, tightness upon waking, discomfort after cleansing. The Atobarrier365 line is specifically designed for sensitive and dry skin, with skin lipids like ceramides that strengthen the damaged barrier..
• Post-dermatological treatment skin : after microneedling, light peeling, or fractional laser — reduces hydration loss, visible redness, and roughness..
• Eczema-prone skin : recognized by the National Eczema Association, tested non-comedogenic on 20 adults with acne-prone or sensitive skin.

⚠️ Avoid if : you are looking for a powerful anti-aging effect (prefer Regederm365 from the same brand), or if you have oily skin that cannot tolerate any moisturizing active ingredients (opt for Theracne365).

Results develop in stages, depending on your epidermis's ability to restore its lipid reserves:

From the first application : immediate sensation of comfort, disappearance of tightness. Instrumental study on 32 women shows immediate results after a single application.

After 1 week : smoother skin texture, reduction of microcracks invisible to the naked eye. The epidermis retains water better between applications.

After 4 weeks of daily use : 38% improvement in the skin's natural ability to defend itself against aggressions, +132% perceived improvement in hydration and +152% improvement in dryness according to self-assessment on 32 women. The lipid barrier gradually rebuilds.

Prolonged hydration : hydrating effect lasting up to 72 hours, which means that even if you skip an application, your skin keeps a reserve.

Note: this is not a medical treatment. If your eczema or atopic dermatitis is severe, consult a dermatologist before using this product.

What is the difference between this ampoule and a classic hyaluronic acid serum?

Most HA serums hydrate the surface but do not strengthen the barrier. Here, the new generation hyaluronic acid is combined with ceramides that have an intrinsic moisture-retention capacity, helping to retain hydration longer.It is the patented AMOREPACIFIC technology that stabilizes the insoluble ceramides in an aqueous formula.

Can I use it with other active ingredients (retinol, AHA, BHA)?

Yes, and it is even recommended. Ceramides repair the barrier damaged by chemical exfoliants or retinol. Apply your active treatment first (wait 10 minutes), then the Cera-HA ampoule to limit irritation. The product is dermatologically tested (48-hour patch test), non-comedogenic (4 weeks on 20 adults with acne), and tested on sensitive skin panels (4 weeks)..

How long does a 30 ml bottle last?

With 2-3 drops morning and evening, expect about 6 to 8 weeks of use. Some users find the volume a bit small given the price,but the concentration of active ingredients justifies the compact size.

Does the texture feel sticky? Can I apply makeup over it?

No. The texture is quite fluid and can run easily,, it contains hyaluronic acid which gives a slightly slippery sensation, but it absorbs well into the skin.. It does not leave a sticky finish and contains no irritating ingredients.Ideal under foundation.

Can I use this ampoule if my skin is already oily?

Dehydrated oily skin often feels tight and uncomfortable, even if it looks shiny on the surface — AESTURA recommends effective hydration without clogging pores.The ampoule is non-comedogenic and lightweight, so it is compatible.

Do I have to use the Atobarrier 365 cream afterward?

No, but it is the duo optimized by the brand. For optimal results, use it with the Atobarrier365 cream.If you prefer a gel texture, the Hydro Soothing Cream from the same range also works. The key is to seal the ampoule with an emulsion or occlusive cream.

AESTURA is the number one brand recommended by dermatologists in Korea for sensitive skin. Born from over 40 years of dermatological and scientific research, it belongs to the AMOREPACIFIC group and builds on its pharmaceutical heritage to develop targeted dermocosmetic solutions.

The Atobarrier365 line is based on a clinical discovery: sensitive skin has shorter and fewer ceramides, creating gaps in the barrier that cause dryness. AESTURA has therefore developed a patented ceramide capsule technology that has demonstrated 190% better retention after cleansing compared to formulas without capsules.

The brand manages its own R&D laboratory (AESTURA Derma Lab) with over 470 fundamental research publications and 240 patents on ingredients and technologies optimized for specific skin issues. Their approach: understanding the specific causes of sensitivity rather than masking symptoms.

To explore all of AESTURA’s expertise in barrier repair and dermatological hydration: Discover the entire AESTURA range.

Complete INCI (official AESTURA source):

Water/Aqua/Eau, Butylene Glycol, Glycerin, Niacinamide, 1,2-Hexanediol, Betaine, Panthenol, Carbomer, Ethylhexylglycerin, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Cellulose Gum, Tromethamine, Sodium Trimetaphosphate, Dipotassium Glycyrrhizate, Propanediol, Adenosine, Hydroxypropyl Bispalmitamide MEA, Sodium Metaphosphate, Glyceryl Caprylate, Potassium Hydroxide, Sodium Lactate, Biosaccharide Gum-1, Caprylic/Capric Triglyceride, Pentylene Glycol, Citric Acid, Hydroxyethyl Urea, Polyglyceryl-10 Stearate, Cholesterol, Propylene Glycol, Potassium Cetyl Phosphate, Tocopherol, Ceramide NP, Mannitol, Stearic Acid, Silica, Acrylates/Ammonium Methacrylate Copolymer, Hydrogenated Lecithin, Palmitic Acid, Oleic Acid, Arachidic Acid, Sphingolipids.

Clean formulation : free from parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, SLS & SLES sulfates, triclocarban, triclosan, and contains less than 1% synthetic fragrance.

Focus on the triple lipid complex : Cholesterol + Ceramide NP + Fatty acids (Palmitic, Stearic, Oleic, Arachidic Acid) → biomimetic trio that replicates the lamellar structure of the stratum corneum. Sphingolipids (a family that includes ceramides) help reinforce this architecture.

AESTURA uses a patented encapsulation technology to stabilize these lipids in an aqueous base — this allows the ampoule to remain fluid while delivering ceramides that are usually insoluble in water.