Apply the ISOI Blemish Care Up Serum morning and evening on clean skin, after your lotion/toner. Dispense 2 to 3 pumps into the palm of your hand, then gently pat over the entire face, focusing on marked areas (spots, acne scars). Allow it to fully absorb before applying your moisturizer, and don’t forget sunscreen during the day to enhance the anti-spot effect.