Cica PDRN Repair Cream — Crème Micro-Capsules ADN Saumon

This cream combines five cellular repair technologies in a biomimetic formula designed for tired skin.

Sodium DNA (PDRN) — salmon DNA fragments purified to 95% according to marine biotechnology protocols. DNA fragments (molecular weights 50–1500 kDa) activate adenosine A2A receptors to stimulate tissue regeneration, collagen synthesis, and reduce inflammation. When applied topically, the effect is gradual but well tolerated, even on reactive epidermis.

7 Peptide Complex — short amino acid chains that target elasticity and epidermal density where sagging begins. This complex helps improve skin elasticity and density while targeting areas prone to sagging and fine lines..

10 Types of Hyaluronic Acid — a high-hydration formula combining 10 varieties of different molecular weights for deep hydration and barrier strengthening. From very high weight (surface hydration) to low weight (intercellular penetration), each molecule works at its level.

Niacinamide (vitamin B3) — regulates complexion, slows sebum overproduction, supports endogenous ceramide synthesis.

Centella Asiatica Extract + 4 active derivatives (madecassoside, asiaticoside, madecassic acid, asiatic acid) — the pentacyclic centellosides stimulate the synthesis of glycosaminoglycans (GAG) and endogenous hyaluronic acid in the dermis, providing a soothing effect documented on eczema and micro-inflammations.

5 Types of Ceramides — structural lipids that strengthen the skin barrier and improve overall complexion, reducing transepidermal water loss (TEWL).

A gel-cream texture with micro-capsules that burst under your fingers: that's what makes this formula addictive. The capsules gently dissolve upon application, allowing a balanced absorption of oil and hydration for a smooth, non-sticky finish..

☀️ Morning routine

1. Cleanse your face (micellar water or pH-balanced foam)
2. Apply your usual toner/essence
3. Take a small amount of BEPLAIN cream, warm it between your palms
4. Gently press onto face and neck — the capsules melt on contact with skin heat
5. Let absorb for 1-2 minutes before your SPF50+ sunscreen

🌙 Evening routine

1. Double cleanse (oil then foam)
2. Toner + active serum(s) if you use them (PDRN layers very well with acids and retinol))
3. Apply the cream in a generous layer: it can be used as a daily cream or as an occlusive overnight mask
4. As a sleeping pack, leave on all night without rinsing

Frequency: every day. In winter or after a peel, double the amount at night for intensive repair.

This biomimetic cream is designed for several skin types:

• Tired, dull skin, losing elasticity — PDRN and 7 peptides boost cell regeneration noticeable within 3-4 weeks
• Sensitive, reactive skin prone to redness — the Centella + panthenol complex soothes micro-inflammations without irritation. Fragrance-free, alcohol-free formula, tested on sensitive skin
• Chronically dehydrated skin — 10 hyaluronic acids + ceramides rebuild the lipid barrier and reduce transepidermal water loss
• Mature skin (35 years and older) seeking a gentle alternative to retinoids — PDRN stimulates collagen synthesis without photosensitization or peeling
• Post-aesthetic treatments (microneedling, peels, laser) — salmon DNA accelerates healing and reduces residual erythema

Avoid if: known allergy to seafood (although the DNA is highly purified, precautionary principle). No documented contraindication for pregnancy/breastfeeding, but consult your dermatologist if you are pregnant.

Salmon DNA doesn't work miracles instantly — it teaches your skin how to repair itself better, cell by cell.

From 1 week: the epidermis regains its comfort, post-cleansing tightness disappears. The capsule texture leaves a velvety finish without a greasy film.

After 2-3 weeks: skin texture refines, diffuse redness fades. The bounce-back effect (touch resilience) improves thanks to peptides and PDRN.

After 4-6 weeks of continuous use: dehydration fine lines fill in, complexion gains even brightness. Preliminary cosmetic studies have shown measurable improvements in wrinkle depth, hydration, and overall elasticity after PDRN treatment..

Prolonged use (8-12 weeks): skin density improves, especially in delicate areas (eyelids, neck). The complexion becomes more even thanks to niacinamide.

Important note: topical PDRN works more gradually than clinical injections like Rejuran, but without needles or downtime. Patience and consistency are your allies.

What is the difference with the Cica PDRN Skin Booster Serum from the same range?

The serum is more fluid, absorbs quickly, and is worn under your usual cream—perfect for layering actives. The Repair Cream is richer, contains ceramides, and can replace your moisturizer or be used as an overnight mask. If you want to maximize the PDRN effect, use both: serum in the morning + cream at night.

Are the pink capsules just a marketing gimmick?

No: they encapsulate liposoluble actives (nourishing oils) that merge with the water-soluble actives in the gel upon application, ensuring a fresh emulsion and gradual release. It’s a stabilization technology, not a visual gimmick.

How long does a 50 ml jar last?

Between 6 and 8 weeks with daily use morning + night (a hazelnut-sized amount per application). If you use it only at night or as a sleeping pack 3-4 times a week, it easily lasts 3 months.

I’m vegan, can I use this product?

PDRN is of marine animal origin (salmon DNA), so the cream is not vegan. BEPLAIN offers other 100% plant-based lines (Mung Bean, Chamomile). If animal ethics are a priority, consider these alternative ranges.

Can I use it with acids (AHA/BHA) or retinol?

Yes, excellent tolerance. Apply your exfoliating actives or retinol first (after toner), let absorb for 5 minutes, then seal with the Repair Cream. It soothes and limits irritation caused by acids. Just avoid mixing directly in the palm.

Is the cream suitable for oily/acne-prone skin?

It is non-comedogenic and niacinamide regulates sebum, but the texture remains quite rich. If you have very oily skin, reserve it for the evening or focus on dry areas (cheeks, eye contour). Combination skin loves it for overall use.

BEPLAIN is one of the most popular cruelty-free Korean brands, specializing in simple yet effective formulas with a handful of carefully selected, safe, natural, and EWG Green Safe certified ingredients. The name "BEPLAIN" sums up the philosophy: to be transparent, pure, and honest.

Founded in 2018, the brand relies on massive consumer data through an exclusive partnership with Hwahae, Korea's largest beauty app (10 million active users). Their first products — the Greenful pH-Balanced Cleansing Foam and the Cicaful Ampoule — were created based on real customer insights. It’s skincare driven by data above all.

On the environmental side, BEPLAIN takes sustainability seriously: biodegradable packaging made from sugarcane bagasse, plant-based and sustainable ingredients, reef-safe sun care products. The Mung Bean line has even won more than 20 beauty awards in Korea.

With this Cica PDRN Repair Cream, BEPLAIN takes a technological leap by incorporating marine biotechnology (salmon DNA) while staying true to its clean and accessible values.

Discover the entire BEPLAIN range

Complete INCI formula (44 ingredients):

Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii (Shea) Butter, Squalane, Niacinamide, Simethicone, 1,2-Hexanediol, Cetearyl Alcohol, Polyglyceryl-2 Stearate, Arachidyl Alcohol, Glyceryl Stearate, Butylene Glycol, Stearyl Alcohol, Behenyl Alcohol, C12-16 Alcohols, Arachidyl Glucoside, Carbomer, Tromethamine, Ethylhexylglycerin, Palmitic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Hydrogenated Lecithin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Xanthan Gum, Adenosine, Coccinia Indica Fruit Extract, Solanum Melongena (Eggplant) Fruit Extract, Amber Powder, Curcuma Longa (Turmeric) Root Extract, Ocimum Sanctum Leaf Extract, Centella Asiatica Extract, Sodium DNA (PDRN), Glucose, Corallina Officinalis Extract, Moringa Oleifera Seed Oil, Aloe Barbadensis Flower Extract, Simmondsia Chinensis (Jojoba) Seed Oil, Madecassoside, Asiaticoside, Madecassic Acid, Centella Asiatica Leaf Extract

Repairing actives: Sodium DNA (PDRN, salmon DNA fragments 50-1500 kDa), 7-peptide complex (not detailed on public INCI but mentioned in formulation), adenosine (anti-wrinkle by collagen stimulation).

Multi-level hydration: 10 types of hyaluronic acid (not individually listed, patented encapsulated technology), glycerin, plant squalane, shea butter.

Soothing botanicals: Centella asiatica (leaf extract + 4 purified centellosides), holy basil (Ocimum Sanctum), turmeric, aloe, red algae Corallina extract.

Lipid barrier: 5 types of ceramides (encapsulated technology, not detailed on INCI), hydrogenated lecithin, jojoba and moringa oils.

Texture & stability: Carbomer (gelling agent), simethicone (anti-foam), emollient fatty alcohols (cetearyl, stearyl, behenyl — non-drying), amber powder (pearlescent capsule effect).

Free of synthetic fragrance, denatured alcohol, parabens, sulfates. Clean formula validated EWG Green Safe according to BEPLAIN standards.