CENTELLIAN 24 Lifting Peptide Cream — Soin Raffermissant 43 Peptides

This cream combines a dense molecular architecture designed to restore firmness.

Complex of 43 peptides (including Tripeptide-1, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8): bioactive fragments that mimic collagen degradation signals. The skin responds by increasing its production of extracellular matrix — type I and III collagen, elastin — to compensate for this simulated loss. Result: dermal density rises, and wrinkles fill in.

5 hydrolyzed plant proteins (wheat, soy, rice, oat, corn): broken down into small peptides, they penetrate the stratum corneum and provide ready-to-use amino acids. Unlike whole proteins that remain on the surface, these fragments directly nourish fibroblasts.

Niacinamide (Vitamin B3): regulates ceramide synthesis and slows trans-epidermal water loss. At the same time, it reduces post-inflammatory discolorations and evens out mature skin tone.

Adenosine : this anti-wrinkle active ingredient recognized by the KFDA stimulates elastin production and reduces the depth of established wrinkles. A perfect complement to peptides for lasting mechanical action.

Centella Asiatica Extract + Beta-Glucan : a soothing duo that calms low-grade inflammation, common in fragile mature skin. Beta-glucan also strengthens local skin immunity.

Squalane : a biomimetic emollient (plant-derived from natural squalene) that restores the hydrolipidic film without clogging. Penetrates without leaving a greasy finish.

☀️ Morning routine

1. After toner and serum, take a small amount of cream on a clean spatula.
2. Warm the texture between your palms for 3-4 seconds: it becomes more fluid and absorbs better.
3. Apply with upward presses — from the chin to the temples, from the center of the face outward — to stimulate microcirculation and enhance the lifting effect.
4. Focus on areas with wrinkles (forehead, nasolabial folds, facial contour).
5. Wait 60 seconds before applying SPF50+ sunscreen.

🌙 Evening routine

1. On cleansed and toned skin, first apply your active treatments (retinol, azelaic acid, stabilized vitamin C).
2. Wait 5 minutes to avoid interactions.
3. Apply the Lifting Peptide Cream generously: at night, the skin can absorb a richer texture.
4. To boost the effect, perform a lifting massage: press firmly with your thumbs along the jawbone, from the chin to the ears, 5 times. Redefine the facial contour.

Frequency: daily. The peptide complex requires regular exposure to maintain the biochemical signal.

This cream is intended for the following profiles:

• Mature skin (35-55 years old) that loses firmness, with deepening expression lines and sagging contours. The 43 peptides boost structural synthesis.
• Normal to dry skin that can tolerate a velvety, semi-rich texture. If you have combination skin, reserve it for dry areas (cheeks, temples) or use it only at night.
• Fans of multi-step K-beauty routines looking for a nourishing final cream compatible with serums and active ampoules.
• Skin post-aesthetic treatment (peeling, LED, microneedling): peptides and centella promote regeneration without irritation.
• Users of retinol who need a soothing and repairing cream to counterbalance induced dryness.

Avoid if:

• Oily skin with active blemishes: the texture may be too rich and clog pores.
• Fragrance sensitivity: the formula contains fragrance (although discreet).

Observable results timeline

From 3 days : the velvety texture envelops the skin without a greasy film. Hydration is immediate, and the skin texture feels smoother to the touch. Post-cleansing tightness disappears.

After 2 weeks : the epidermis is plumped, dehydration fine lines fade. The complexion appears more even thanks to niacinamide, which regulates micro-inflammations.

After 4 weeks : expression wrinkles (forehead, crow’s feet) lose depth. The facial contour slightly redefines — a sign that peptides have stimulated the dermal matrix. The skin regains bounce under the fingers.

After 8 weeks : skin density visibly improves. Nasolabial folds are softened, the skin looks firmer, less sagging. The lifting effect stabilizes with continued use.

Important note: peptides do not replace medical anti-aging treatments (retinol, acids, injections). They act as a complement to support the dermal structure.

What is the difference between CENTELLIAN 24's Lifting Peptide Cream and Lifting Peptide Serum?

The serum contains 42 peptides in a light aqueous base, with bifida ferment lysate (probiotic) for quick absorption. The cream, on the other hand, has 43 peptides in a velvety, semi-rich emulsion, with 5 hydrolyzed plant proteins to deeply nourish. Ideal routine: serum under the cream to combine both levels of action.

Can I use this cream with retinol at night?

Yes, it’s even recommended. Apply your retinol (or retinal) on dry skin, wait 5-10 minutes, then seal with the Lifting Peptide Cream. The peptides and centella will buffer potential retinol irritation, while squalane restores the lipid barrier. Just avoid mixing the two products in your palm: layer them.

Is the texture really “velvety” or does it leave a sticky finish?

Truly velvety. The formula combines volatile silicones (cyclopentasiloxane) that evaporate after application and non-greasy emollients (neopentyl glycol diheptanoate). Result: a powdery-silky feel, absorption in 30-40 seconds, zero residue. Makeup compatible after 1 minute.

How long does the 65 ml jar last with daily use?

About 3 to 4 months if you use a hazelnut-sized amount morning and evening (face + neck). The rich texture means you use little: it spreads easily and covers well. If you only use it at night, expect 5-6 months.

Can I use it around the eyes or do I need the dedicated eye cream?

You can gently tap a micro-dose around the eye (orbital bone only, not the mobile eyelid). But if you have puffiness or dark circles, the Lifting Peptide Eye Cream 15ml is more targeted: it contains 42 peptides + specific ceramide NP for this delicate area. The face cream remains a good economical option for a problem-free eye contour.

Does the cream contain TECA, CENTELLIAN 24’s signature ingredient?

No, this Lifting Peptide line focuses on peptides and plant proteins, with classic centella asiatica extract (no standardized TECA). For high-concentration TECA, go for the brand’s Madeca Cream Time Reverse line, which contains 30,000 ppm TECA. The two lines complement each other: Madeca to soothe and regenerate, Lifting to firm and smooth.

Founded by Dongkook Pharmaceutical, a Korean pharmaceutical group active since 1968, CENTELLIAN 24 is a derma-cosmetic brand whose name signifies continuous 24-hour care, focused on the restorative virtues of Centella Asiatica. The brand incorporates over five decades of pioneering expertise in centella research.

If the flagship range Madeca relies on TECA (Titrated Extract of Centella Asiatica), a refined and powerful form of centella known for its anti-inflammatory, healing, and barrier-repairing properties,the Lifting Peptide line takes an architectural turn: it uses multi-chain peptide complexes (up to 43 types) and hydrolyzed plant proteins to boost collagen and elastin synthesis. A structural anti-aging approach, whereas Madeca focuses on soothing and regeneration.

CENTELLIAN 24’s approach appeals to Korean dermatologists for its formulation rigor: functionally dosed actives, textures designed for daily use, and systematic irritation testing. The brand does not play the “all-natural” marketing card but opts for reasoned cosmetics inspired by pharmaceutical protocols.

Discover the entire CENTELLIAN 24 range

Complete INCI (official source):

WATER, NEOPENTYL GLYCOL DIHEPTANOATE, GLYCERIN, METHYLPROPANEDIOL, HYDROGENATED POLYISOBUTENE, POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE, CETYL DIMETHICONE, HYDROGENATED POLYDECENE, PHENYL TRIMETHICONE, NIACINAMIDE, GLYCERYL STEARATE, CYCLOPENTASILOXANE, CETYL ALCOHOL, PENTAERYTHRITYL DISTEARATE, DIMETHICONE, DICAPRYLYL ETHER, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, TROMETHAMINE, FRAGRANCE, ETHYLHEXYLGLYCERIN, DIPROPYLENE GLYCOL, PROPANEDIOL, ECLIPTA PROSTRATA LEAF EXTRACT, LAMINARIA JAPONICA EXTRACT, BUTYLENE GLYCOL, ADENOSINE, DISODIUM EDTA, MELIA AZADIRACHTA FLOWER EXTRACT, MELIA AZADIRACHTA LEAF EXTRACT, HYDROGENATED LECITHIN, CURCUMA LONGA (TURMERIC) ROOT EXTRACT, OCIMUM SANCTUM LEAF EXTRACT, POLYSORBATE 20, FRUCTOOLIGOSACCHARIDES, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, SODIUM STEAROYL GLUTAMATE, ACMELLA OLERACEA EXTRACT, BETA-GLUCAN, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, FICUS CARICA (FIG) FRUIT EXTRACT, CENTELLA ASIATICA EXTRACT, SQUALANE, CORALLINA OFFICINALIS EXTRACT, HYDROLYZED HYALURONIC ACID, HYDROLYZED WHEAT PROTEIN, HYDROLYZED SOY PROTEIN, HYDROLYZED RICE PROTEIN, HYDROLYZED CORN PROTEIN, HYDROLYZED OAT PROTEIN, SORBITAN ISOSTEARATE, [43-type peptide complex not detailed]

Key functional actives to note:

• Niacinamide : vitamin B3, barrier regulator + complexion unifier
• Adenosine : KFDA functional anti-wrinkle active, stimulates elastin
• 43-peptide complex : bioactive signals to reactivate collagen/elastin
• 5 hydrolyzed plant proteins (wheat, soy, rice, corn, oat): bioavailable amino acids
• Centella Asiatica Extract : soothing triterpenoids (asiaticoside, madecassoside)
• Beta-Glucan : immunomodulating polysaccharide, strengthens skin defense
• Squalane : plant biomimetic emollient, non-comedogenic
• Acmella Oleracea Extract : plant “botox-like” (spilanthol), relaxes micro-contractions
• Hydrolyzed Hyaluronic Acid : fragmented hyaluronic acid, penetrates better than classic form

Note: the exact peptide list (43 types) is not publicly detailed by the brand, but Incidecoder analyses confirm the presence of Tripeptide-1, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1 among others.