Rejuran & PDRN: The Korean Secret for Regenerated Skin
If you follow the world of Korean cosmetics, you have surely heard of Rejuran. Born in 2013 from the Korean pharmaceutical laboratory PharmaResearch, the brand is now an absolute reference in regenerative medico-cosmetics — first practiced in aesthetic dermatology clinics in Gangnam, then found at home in topical form. Rejuran popularized the famous “Rejuran Healer”, this injectable PDRN treatment that became a signature among Korean actresses for its “baby skin” effect, before expanding its philosophy into a mainstream cosmetic range.
At Ma Petite Corée, based in Seoul since 2017, Rejuran has been one of the brands we have followed from the start. We now have 24 Rejuran references in our catalog, covering all official ranges: Turn Over (premium anti-aging with concentrated c-PDRN), Derma Healer Moisture (deep hydration routine), Derma Healer Pore Tightening (targeted pore action), Biome Healer (2024 microbiome innovation), Triple Radiance (radiance serum), and daily care (iconic masks, balm, cleanser, SPF). In this article, we take an in-depth look at the brand: its clinical origin, its signature PDRN technology, its flagship ranges in detail, and our favorite selection available in stock.
Rejuran: from PharmaResearch laboratory to mainstream cosmetics
The history of Rejuran begins in 2013, when the Korean laboratory PharmaResearch (one of the leaders in regenerative pharmacology in Asia) launched the medical product Rejuran Healer, an injectable “skin booster” based on PDRN (polydeoxyribonucleotide). PDRN is a molecule extracted from salmon reproductive tissues, whose DNA has about 96% similarity with human DNA. This unique biological compatibility means the skin recognizes the molecule as close to its own and uses it as cellular repair material — hence the spectacular regenerative effect when injected.
In just a few years, the Rejuran Healer became the signature aesthetic treatment of Gangnam clinics in Seoul, sought after for its "baby skin" effect without resorting to botulinum toxins or classic hyaluronic acids. K-drama actresses, K-pop idols, and Korean estheticians have made it their favorite anti-aging protocol. Due to the enthusiasm, PharmaResearch decided to expand the use of PDRN to mass-market topical cosmetics — allowing all Korean women (and men) to benefit from the brand's active ingredients without going through clinical treatment. This is how the Rejuran cosmetic line was born around 2019, which later developed with several thematic lines.
Today, Rejuran is one of the most respected skincare brands in Korea, distributed at Olive Young, Korean pharmacies, and premium cosmetic chains. The brand has obtained several patents on its PDRN extraction and stabilization processes, ensuring superior quality compared to generic brands that followed the trend. All our Rejuran products come directly from official distributors in Korea — see our complete Rejuran collection with the 24 references currently in stock.
Rejuran's signature c-PDRN: a patented technology
What sets Rejuran apart from all the cosmetic brands that have ridden the PDRN trend in recent years is its original medical expertise. While classic cosmetic brands add PDRN to existing formulas to meet demand, Rejuran starts from PDRN and builds its formulas around it. This pharmaceutical approach results in a significantly higher concentration of active PDRN compared to competitors (up to 0.5% c-PDRN in the Triple Radiance line, where most competitors use 0.1-0.2%), optimal compound stability, and maximum bioavailability thanks to proprietary encapsulation technologies.
The c-PDRN is the brand's signature technology — a concentrated and purified version of classic PDRN, optimized for topical skin penetration. The Triple Radiance Ampoule c-PDRN 0.5% (€64.90) is the flagship product that pushes this technology to the max, with a visible radiance effect from the first applications. The more recent Turn Over line also applies c-PDRN in formulas dedicated to cell renewal and firmness — the Turnover Ampoule (€48.90) is the historic bestseller, with its Dual Effector version (€53.90) for skin that needs an extra boost.
For those who want to experience the effectiveness of c-PDRN in a complete routine, the Turn Over Set Ampoule + Cream (€74.90) offers the two flagship steps with significant savings compared to buying separately. And to reach the top of the range, the Recover Healer Firming Cream (€85.90) combines c-PDRN and firming actives for a marked lifting effect — especially recommended for mature skin (40+) seeking a cosmetic alternative to injections.
The Turn Over range: Rejuran’s anti-aging pinnacle with c-PDRN
The Turn Over range is Rejuran’s premium anti-aging line and its best ambassador in terms of effectiveness/price ratio in the regenerative skincare segment. It is aimed at mature skin (35 years and older) and skin damaged by time, stress, or active treatments (retinol, peels) seeking to regain firmness, bounce, and even skin tone. The entire range is based on c-PDRN concentration and also includes the latest Triple Radiance innovation for radiance profiles. Here is our selection of the 6 key products.
The Derma Healer Moisture range: deep hydration routine
While the Turn Over range targets premium anti-aging, the Derma Healer Moisture range meets another need: deep and lasting hydration for dehydrated, sensitive, or seasonally damaged skin (air conditioning in summer, heating in winter, intense sun). This range offers a complete 5-step routine — from Bubble Cleansing Water to Moisture Cream — all formulated with PDRN and multi-weight hyaluronic acid to ensure rehydration across all layers of the skin. It is a range particularly suited for young skin (25-35 years) who want to start Rejuran without diving directly into the premium Turn Over.
Derma Healer Pore + Biome Healer: tightened pores and balanced microbiome
For targeted concerns, Rejuran offers two complementary ranges. The Derma Healer Pore Tightening range specifically addresses enlarged pores and uneven skin texture — the Pore Tightening Ampoule (€55.90) visibly tightens pores in a few weeks, and the Pore Tightening Toner Pads (€32.90, 60 pads) provide a convenient alternative for a more subtle daily effect.
The Biome Healer range is Rejuran's 2024 innovation: it combines signature PDRN and probiotics to rebalance the skin microbiome — the ecosystem of beneficial bacteria on the skin's surface. This range is designed for reactive, irritated, and disturbed skin caused by aggressive treatments or a polluted environment. The Youth Formula Ampoule (€56.90) and Youth Formula Cream (€46.90) form the reference duo, complemented by a Youth Formula Sunscreen (€30.90) that combines SPF and microbiome maintenance — perfect for the urban daily routine.
Daily Rejuran care: iconic masks, balm, cleansing, UV
Beyond the complete ranges, Rejuran offers several cult products to use as a complement or as an entry point into the brand. The Healing Mask (€7.90) is probably the most accessible and iconic Rejuran product — a sheet mask soaked in an ultra-concentrated PDRN essence, perfect for an express boost before an event or as an intensive treatment. The Perfect Healing V-Tighter Mask (€42.90), more premium, is the sculpting mask that targets jawline and facial contour definition — a must-have for Korean actresses before filming.
For daily use, the Healer Calming Lip Balm (€33.90) applies the PDRN philosophy to the lip contour with an intense repairing effect, ideal for chapped lips or lips damaged by traditional balms. The Refining Foam Cleanser (€33.90) is the gentle cleanser designed not to disrupt the PDRN actives applied afterward. The Healer UV Protection Balm (€34.90) offers sun protection enriched with Rejuran’s regenerative components. And at the top, the Premium Beauty Device (€1199.90) is the official LED + EMS device that maximizes the penetration of Rejuran treatments — the ultimate investment for enthusiasts who want to replicate the clinical experience at home.
How to integrate Rejuran into a Korean skincare routine?
Here is the typical Rejuran routine we recommend to our clients based on their profile. For young, dehydrated skin (25-35 years): start with the Derma Healer Moisture range in daily routine (cleanser → toner → essence → cream), with a Healing Mask 2-3 times per week. For mature skin (35+) seeking a strong anti-aging effect: Turn Over Set as the core evening routine + Triple Radiance Ampoule c-PDRN 0.5% in the morning for radiance, complemented by the V-Tighter Mask as a weekend treatment. For reactive or problematic skin: the Biome Healer range in duo (ampoule + cream) to rebalance the microbiome before introducing other actives.
How long before seeing results? The first visible effects of topical PDRN usually appear after 3 to 4 weeks of regular use — plumper skin, more even complexion, deeper hydration feeling. Effects on the deep skin texture (reduction of post-inflammatory acne scars, refinement of skin grain, noticeable firmness improvement) require 6 to 12 weeks of continuous use. Rejuran is designed as a long-term treatment, not a marketing quick fix. For skin damaged by active treatments, soothing effects can be visible from the first week thanks to the anti-inflammatory power of PDRN.
Why buy Rejuran at Ma Petite Corée?
Rejuran is one of the most counterfeited skincare brands in the world — its success has attracted a multitude of more or less convincing copies on international marketplaces (AliExpress, Amazon third-party sellers, some Yesstyle sites). Buying through official channels is not a luxury, it is an absolute condition to benefit from the real formulation with concentrated c-PDRN. At Ma Petite Corée, we import each Rejuran product directly from Korea from official PharmaResearch distributors. Our team based in Seoul checks each batch before shipping to guarantee absolute authenticity. Our stock is based in mainland France, which eliminates customs fees for the European Union and allows fast delivery within 3 to 5 business days.
Our differentiating strength compared to French-speaking competitors is our physical presence in Seoul. We follow Rejuran’s new releases in advance (notably the developments of the Biome Healer range and the limited Turn Over editions), purchase exclusive Korean new products that often do not cross borders, and test the products on site before adding them to the catalog. This on-the-ground presence also allows us to offer prices often more competitive than official European stores — Olive Young Global distribution applies export prices 30-50% higher than the domestic Korean market.
Rejuran embodies the best of K-beauty in the medico-cosmetic segment: a brand born from a serious pharmaceutical laboratory, founded on patented technology (PDRN and c-PDRN), supported by real clinical success (the injectable Rejuran Healer used in clinics since 2013), and developed into topical cosmetics with rare consistency on the market. Whether you are discovering the brand or already loyal, find the entire Rejuran collection on Ma Petite Corée — 24 references currently in stock in Seoul.
Also explore our other Korean high-end cosmetic brands in our LUXE collection, our Korean skincare selection, and discover our new arrivals imported from Seoul every week.
— Jihyun, team Ma Petite Corée