REJURAN Turnover Ampoule — Sérum c-PDRN 0,5% Régénérant

c-PDRN 0.5% (Hydrolyzed DNA): this patented marine-derived active ingredient stimulates endogenous collagen production and accelerates cellular repair. Derived from purified salmon DNA fragments, it improves skin elasticity and density — a clinical ingredient now accessible for daily use.

Niacinamide (vitamin B3): this versatile active unifies skin tone, reduces the appearance of pigmentation spots, and controls shine. In synergy with c-PDRN, it refines texture and promotes an even glow.

Sodium Hyaluronate : a low molecular weight form of hyaluronic acid, capable of penetrating deeply to retain water in the epidermis. Plumps and smooths dehydration fine lines in just a few applications.

Adenosine : an anti-aging active recognized by the Korean KFDA, it boosts collagen synthesis and visibly reduces established wrinkles. A perfect complement to PDRN for a lasting smoothing effect.

Organic botanical extracts (mulberry, blueberry, licorice, calendula): a soothing and antioxidant base that calms redness and protects skin DNA from oxidative stress.

☀️ Morning routine

1. Cleanse your face, then apply your usual toner to prepare the skin.
2. Place 3 to 5 drops of the ampoule on clean fingertips and gently massage onto the face, neck, and décolleté, avoiding the eye area..
3. Let the serum fully absorb before applying your moisturizer and mandatory sunscreen..

🌙 Evening routine

1. Follow the same protocol after double cleansing and toner.
2. For optimal results, use the ampoule once or twice a day. — evening use is ideal to maximize nighttime regeneration.
3. You can also apply it to the backs of your hands for a targeted anti-aging effect..

This ampoule is intended for:

• Mature skin looking to improve firmness and visibly reduce established wrinkles.
• Skin damaged by dermatological treatments (laser, chemical peel) requiring accelerated recovery.
• Dehydrated skin seeking a tangible improvement in suppleness and texture.
• People wishing to reduce acne scars, sunspots, or enlarged pores.

Avoid if:

• You have open wounds or active lesions on your face.
• You notice redness, itching, or swelling — consult a dermatologist before continuing.

After 2 weeks of twice-daily use: the skin recovers faster, burn scars (including post-laser) show visible improvements according to a study by the Korea Institute of Dermatological Science conducted on 22 participants.

Improvement in skin density: the epidermis regains firmness and resilience, wrinkles appear less pronounced.

Increased hydration level with an immediate smoothing effect on skin texture and grainOver the weeks, the complexion becomes more even and naturally radiant.

What is the difference between c-PDRN and classic PDRN?

c-PDRN (cosmetic PDRN) is a purified and patented form by REJURAN, optimized for maximum skin penetration and tolerance in daily topical use. It retains the regenerative properties of injectable PDRN used in clinical dermatology.

Can it be combined with retinol or exfoliating acids?

Yes, but introduce them gradually. Use the REJURAN ampoule in the morning and your retinol in the evening, or alternate days. c-PDRN actually helps repair irritations caused by strong active ingredients..

Is the scent strong?

No. The formula does not contain any fragrance listed at the top of the INCI, the scent is neutral and subtle, typical of serums based on plant extracts.

How long does a 30 ml bottle last?

Using 3 to 5 drops morning and evening, expect about 6 to 8 weeks of use — enough to see the first clinical results.

Can it be used after a microneedling session?

Yes, the ampoule has been clinically tested to accelerate post-treatment healing (laser, peeling). Wait 24-48 hours after the session and follow your practitioner's recommendations.

Is the product suitable for oily skin?

Absolutely. Its fluid texture absorbs quickly without leaving a greasy film, and niacinamide helps control shine and tighten pores..

REJURAN is a South Korean clinical line built around a patented technology: PDRN (polydeoxyribonucleotide), a regenerating active ingredient initially used in aesthetic medicine to repair the skin, boost collagen, and refine texture. The brand has popularized this ingredient by making it accessible in topical form, with a 0.5% concentration in this Turnover ampoule.

REJURAN formulas are clinically studied and tested, combining science and nature to treat damage, redness, wrinkles, and fine lines. The c-PDRN technology was originally developed to treat post-procedure and irritated skin — an expertise now highly praised by dermatologists to revitalize tired complexions and repair damaged epidermis.

Discover the entire REJURAN range

Water, Aloe Barbadensis Leaf Juice, Butylene Glycol, PEG-6, Rubus Fruticosus (Blackberry) Leaf Extract, Glycerin, Niacinamide, Glycyrrhiza Glabra (Licorice) Root Extract, Calendula Officinalis Flower Extract, Vaccinium Angustifolium (Blueberry) Fruit Extract, Morus Nigra Fruit Extract, Sodium Hyaluronate, Hydrolyzed DNA (c-PDRN), Tocopheryl Acetate, Xanthan Gum, Carbomer, Caprylyl Glycol, Polysorbate 20, Hexylene Glycol, Phenoxyethanol, Benzyl Alcohol, (-)-Alpha-Bisabolol, Adenosine, Arbutin, Ethylhexylglycerin.

The formula favors a base of organic plant extracts (blackberry, licorice, calendula, blueberry, black mulberry) to soothe and prepare the epidermis to receive the regenerating active ingredients. Paraben-free, sulfate-free, cruelty-free, formulated without harmful additives.