REJURAN Turn Over Set — Duo Ampoule & Crème ADN Régénérant

This duo concentrates c-PDRN (Polynucleotide) technology at two complementary dosages. The ampoule contains 0.5% c-PDRN (Hydrolyzed DNA), the highest concentration in the range: this active ingredient derived from salmon DNA boosts collagen synthesis and accelerates tissue repair at the cellular level. The cream provides 0.2% c-PDRN to extend the regenerative action.

Niacinamide : present in both formulas, this vitamin B3 strengthens the skin barrier, evens out skin tone, and stimulates ceramide production. Hyaluronic Acid (Sodium Hyaluronate): captures water on the surface and in the deeper layers — the epidermis remains hydrated up to 20% more after four weeks of use.

Adenosine : a natural nucleotide that boosts collagen production and smooths existing fine lines. Botanical Extracts (Glycyrrhiza Glabra, Calendula, Aloe): soothe post-treatment redness (laser, peeling) and reduce inflammation thanks to the glycyrrhizin from licorice.

☀️ Morning routine

1. After your toner, place 3 to 5 drops of the ampoule on your fingertips
2. Gently tap on your face, neck, and décolleté (avoid the eye area)
3. Wait 1 minute for full absorption
4. Apply a small amount of cream with upward massages
5. Finish with your SPF 50+ sunscreen (PDRN can cause slight photosensitivity)

🌙 Evening routine

1. Repeat the ampoule + cream protocol
2. Use the set twice a day for at least 2 weeks to observe the turnover cycle
3. Compatible after a retinol treatment (wait 5 minutes between the two)

One ampoule bottle lasts about 30 days with 4 drops morning and evening.

Target profiles:

• Skin after aesthetic procedures — this duo was formulated to support healing after lasers, chemical peels, or microneedling (wait 48h after the procedure)
• Mature skin (35 years+) seeking to slow density loss and smooth established wrinkles
• Dull or tired complexions : accelerated turnover reveals smoother skin texture in just 2 weeks
• Reactive sensitive skin : formulas without parabens, sulfates, essential oils

To avoid if:

• Known allergy to marine products (salmon DNA)
• Pregnancy/breastfeeding (as a precaution, although no studies report risk)
• Damaged skin or active burns (wait for healing)

After 2 weeks of twice-daily use : visible improvement in the healing of acne marks or superficial burns (tested on 22 volunteers by the Korea Institute of Dermatological Science). The texture becomes softer to the touch.

After 4 weeks : hydration increases by 20%, skin density improves — resulting in fewer visible wrinkles and a face that appears "plumper." The complexion gains brightness thanks to the brightening action of niacinamide and arbutin.

Continuous use (8-12 weeks) : cell turnover balances, pores tighten, and pigment scars gradually fade. No medical claims: this set supports natural regeneration processes and does not replace dermatological treatment.

What is the difference between the ampoule and the cream?

The ampoule contains 0.5% c-PDRN — it is the shock serum that deeply restarts regeneration. The cream provides 0.2% c-PDRN with an emollient base (squalane, shea butter) to lock in hydration and extend the effect. Always use the ampoule first, then the cream on top.

Can I use only one of the two products?

Yes, but the duo protocol optimizes results. If you have to choose: the ampoule for pure regeneration (young skin, limited budget), the cream if you primarily want rich hydration with a plumping effect.

How long before seeing results?

From 1 week, your skin will feel more comfortable and hydrated. Effects on firmness and wrinkles appear after 2 to 4 weeks. To treat scars or pigmentation spots, plan for 8 to 12 weeks of continuous use.

Is this set suitable for oily skin?

The ampoule is light and absorbs quickly — perfect for combination to oily skin. The cream is richer: if you have oily skin, reserve it for the evening or apply a thin layer in the morning. Alternative: replace the cream with an emulsion from the REJURAN range during the day.

Can I combine this set with retinol or acids?

Yes. Apply your AHA/BHA or retinol, wait 5 to 10 minutes, then follow with the REJURAN ampoule. The c-PDRN helps soothe irritations caused by strong actives. Just avoid layering too many actives on the same day if you are a beginner.

Is the c-PDRN really derived from salmon DNA?

Yes. It consists of polynucleotides extracted and purified from salmon milt, used for decades in regenerative medicine. REJURAN’s DOT™ technology optimizes their molecular weight for better skin penetration. Cruelty-free product according to Korean standards.

REJURAN is a Korean dermocosmetic brand launched by Pharma Research, a laboratory specializing in aesthetic and regenerative medicine. Originally, REJURAN developed PDRN injections for dermatology clinics — these "skin boosters" have become iconic in Korea for achieving the famous "glass skin." In 2019, the brand adapted this technology into topical treatments with the Healer range, allowing the use of PDRN at home, without needles or downtime.

The c-PDRN (Cosmetic Polydeoxyribonucleotide) patent combines salmon DNA with a DOT™ fractionation method that reduces molecule size to penetrate the skin barrier. Since March 2026, REJURAN has been distributed in 380 Sephora stores across the United States — a sign of its international recognition. In France, the brand appeals to fans of scientific K-beauty, far from empty marketing promises.

Discover the entire REJURAN range

REJURAN Turn Over Ampoule (30 ml)

Water, Butylene Glycol, PEG-8, Niacinamide, Glycereth-26, Glycerin, 1,2-Hexanediol, Licorice Root Extract (licorice), Vaccinium Angustifolium Fruit Extract (blueberry), Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Hydrolyzed DNA (c-PDRN 0.5%), Sodium Hyaluronate, Polysorbate 20, Tocopheryl Acetate (vitamin E), Bisabolol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Adenosine, Arbutin, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin.

REJURAN Healer Turnover Active Cream (50 ml)

Water, Glycerin, Butylene Glycol, Dipropylene Glycol, Niacinamide, Hydrolyzed DNA (c-PDRN 0.2%), Sodium Hyaluronate, Ceramide NP, Squalane, Panthenol, Urea, Serine, Trehalose, Adenosine, Tocopheryl Acetate, Bisabolol, Algin, Pullulan, Glyceryl Polyacrylate, Hydrogenated Lecithin, Cetearyl Glucoside, Carbomer, Disodium Phosphate, Potassium Phosphate, Phenoxyethanol, 1,2-Hexanediol.

Formulas without parabens, sulfates, or essential oils. Dermatologically tested. Mild preservatives (Phenoxyethanol + Caprylyl Glycol).