MEDICUBE PDRN Pink Peptide Eye Cream — Soin Regard Régénérant

This treatment targets the eye contour with clinical precision, combining advanced regenerating active ingredients. At the heart of the formula: the PDRN (Polydeoxyribonucleotide), also called Sodium DNA, a salmon DNA fragment compatible with our human cells. Its mission? To stimulate fibroblast activity and support collagen synthesis, restoring firmness and elasticity to this delicate area.

The 10-peptide complex works in synergy: Palmitoyl Pentapeptide-4 promotes collagen production, while Palmitoyl Tetrapeptide-7 limits post-UV inflammation and preserves the extracellular matrix. Copper Tripeptide-1 completes the action by stimulating tissue repair and microcirculation.

The Retinol at 99% purity refines skin texture and plumps fine lines without irritation. Niacinamide (vitamin B3) evens out skin tone and reduces pigmented areas. Finally, caffeine activates lymphatic drainage to reduce puffiness, while turmeric root extract (Curcuma Longa Root Extract) provides soothing and antioxidant benefits.

☀️ Morning routine

1. After toner, take a small amount of cream (equivalent to half a grain of rice per eye)
2. Gently apply around the eye area by tapping with your ring finger, from the inner corner to the temple
3. Let absorb for 30 seconds before your serum or moisturizer
4. Finish with your sunscreen (essential when using retinol)

🌙 Evening routine

1. On cleansed and toned skin, apply the eye care with light tapping
2. Spread the texture up to the orbital bone if you want to treat smile lines or crow's feet
3. Wait 1 minute before applying your serum or night cream

Pro tip: you can use it on other targeted areas (nasolabial folds, forehead) as a complement to your routine.

This cream is designed for several specific profiles:

• Mature skin (30 years and older) : if you notice dehydration fine lines, loss of firmness, or tired-looking eyes despite 8 hours of sleep
• Skin with pronounced dark circles : brownish pigmentation, slow circulation, or shadows related to the thinness of the epidermis
• Fans of clinical actives : you tolerate retinol and are looking for an eye care product that combines regeneration and measurable results
• Sensitive eye contours : thanks to its light texture and soothing agents (adenosine, neem extract), this care is suitable even for reactive skin usually irritated by classic retinols

Avoid if: severe fish allergy (despite PDRN purification, as a precaution), or if you are just starting retinol (begin with an application every 2 days).

The first signs appear as early as the first week: +22.5% hydration and +2.87% firmness around the eye after 7 days of use, according to a clinical test conducted by the Global Institute of Dermatological Sciences.

After 3 to 4 weeks, the contour is visibly smoothed: dehydration fine lines fade, the eyes look rested, and brownish dark circles gradually lighten. The non-greasy texture absorbs quickly without migrating into the eye or overloading the delicate skin.

In the long term (8 to 12 weeks), cell regeneration supported by PDRN strengthens the resilience of the contour: less marking upon waking, better tolerance to screens and fatigue, restored elasticity. This is not an instant miracle — it is a gradual reconstruction of tissue quality.

Can I use it if I have never used retinol before?

Yes, but with caution. The retinol at 99% purity is concentrated, so start by applying it 2 to 3 times a week in the evening. If your skin does not react (no redness, tightness, or mild peeling), you can gradually increase the frequency to daily use.

Is this cream suitable for sensitive eyes or contact lens wearers?

The formula is hypoallergenic tested and contains neither harsh fragrance nor irritating essential oils. It generally does not migrate into the eye if applied at a reasonable distance from the lash line. Contact lens wearers report good tolerance.

What is the difference compared to other MEDICUBE PDRN products (serum, toner)?

The PDRN Pink Cica toner prepares and soothes the entire face. The Pink Peptide serum targets overall radiance. This eye cream is specifically formulated for the periorbital area: richer texture, concentration of anti-wrinkle peptides, retinol dosed for this ultra-thin skin. You can combine them for a complete PDRN protocol.

How long does a 30 ml tube last with daily use?

About 3 to 4 months if you apply it morning and evening on both eyes. The texture is concentrated, so a small amount is enough. Some users also extend it to crow’s feet, which reduces the duration to 2-3 months.

Can it be used during the day, under makeup?

Yes, its light and non-sticky texture does not cause concealer or foundation to cake. However, since retinol is photosensitizing, applying SPF 50+ sunscreen on the entire face (including the eye contour) is essential if you use it in the morning.

Is topical PDRN as effective as injections?

No. PDRN injections (like Rejuran) deliver polynucleotides directly into the dermis for more pronounced results on scars, deep sagging, or hollow dark circles. Topical PDRN works on the surface and as support: hydration, gentle cell regeneration, skin texture improvement. It is complementary, not interchangeable.

MEDICUBE offers solutions for sensitive and blemish-prone skin through various lines targeting dryness, dullness, and pores. Made in Korea, the brand ensures effective treatment at every step of your routine. Among its best-sellers are: Red Capsule Cushion, Zero Pore Pad, Red Concealer, Red Foam Cleanser, and Red Erasing Cream..

The PDRN Pink line follows a cosmeceutical approach: formulas based on clinical actives (PDRN, peptides, high-purity retinol) designed for visible and measurable results. MEDICUBE focuses on transparency: clinical studies, precise concentrations, clear usage protocols. No empty marketing promises — just serious dermocosmetics, accessible and made according to the strict standards of K-beauty.

Discover the entire MEDICUBE range

Full INCI: Water, Glycerin, Dipropylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Cetearyl Alcohol, Glycereth-26, Butylene Glycol Dicaprylate/Dicaprate, Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate, Cetearyl Olivate, Sorbitan Olivate, Propylene Glycol Dibenzoate, Pullulan, 1,2-Hexanediol, Glyceryl Stearate, Vinyl Dimethicone, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Polyisobutene, Butylene Glycol, Ethylhexylglycerin, Propanediol, Melia Azadirachta Leaf Extract, Adenosine, Melia Azadirachta Flower Extract, Curcuma Longa (Turmeric) Root Extract, Sorbitan Isostearate, Sorbitan Oleate, Caprylyl/Capryl Glucoside, Fragaria Chiloensis (Strawberry) Fruit Extract, Hedera Helix (Ivy) Leaf/Stem Extract, Cyanocobalamin (Vitamin B12), Citrus Nobilis (Mandarin Orange) Peel Extract, Retinol, Sodium Hyaluronate, Hydrolyzed Collagen, Ubiquinone (Coenzyme Q10), Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen.

The key active ingredients (PDRN in the form of Sodium DNA, niacinamide, retinol, peptide complex) are positioned in the first half of the list, ensuring an effective concentration. The formula excludes parabens, sulfates, drying alcohols, and harsh essential oils.