Apply the MEDICUBE AGE-R Peptide Mela ampoule on clean skin, right after toner. Dispense 2 to 3 pumps onto the face and neck, then gently massage until absorbed, focusing on problem areas (spots, dullness, wrinkles). Use preferably in the evening, then finish with a moisturizer. In the morning, always follow with sun protection to enhance the anti-spot and anti-aging effects.