Apply the NUMBUZIN No. 9 NAD Collagen Overnight Selfie Patches in the evening, on clean, dry skin, targeting marked areas (wrinkles, forehead lines, nasolabial folds, around the mouth…). Press for a few seconds to ensure they stick well, then leave on overnight while you sleep. Gently remove them upon waking, then continue with your usual skincare routine for a plumped skin effect, like a selfie filter.