ANUA PDRN + Hyaluronic Acid Capsule 100 Serum — Régénération Cellulaire

This serum combines three pillars of skin biology in a highly concentrated formula, encapsulated for optimal penetration.

11 hyaluronic acids (29,049 ppm Hydrolyzed Hyaluronic Acid + 800 ppm Sodium Hyaluronate): a molecular weight gradient—from nano to macro—nourishes every layer of the epidermis. The small molecules (Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate at 1 ppm) reach the deeper layers, while the high-weight forms keep the surface plump.

PDRN / Sodium DNA (100 ppm): purified DNA fragment extracted from salmon sperm, 98% biocompatible with human DNA. Activates adenosine A2A receptors, stimulates collagen synthesis, and accelerates cell turnover. Historically used in regenerative medicine, it is now available topically thanks to advanced encapsulation.

Hydrolyzed collagen + Glutathione : low molecular weight collagen strengthens the extracellular matrix, while glutathione—a antioxidant tripeptide—fights oxidative stress and evens out skin tone over time.

Niacinamide (vitamin B3): regulates sebum production, reduces pigmentation spots, and improves barrier function. Its combination with PDRN enhances natural radiance.

☀️ Morning routine

1. After your toner, place 2 to 3 drops in the palm of your hand (be careful, the fluid texture flows quickly).
2. Warm it between your hands, then pat it all over your face until fully absorbed — the emerald color fades instantly.
3. Follow with your cream then your SPF 30 minimum (PDRN does not cause photosensitivity, but always protect yourself).

🌙 Evening routine

1. Apply 2 drops after cleansing and toner.
2. For a regenerating "sleeping pack" effect: layer 2 to 3 thin coats, letting each absorb before applying the next (Korean layering technique). The next day, your skin is plump and smooth.
3. You can also mix 1 drop with your foundation in the morning for a luminous "glass skin" finish that lasts all day.

• Mature skin (30+) : seeking cellular regeneration, restored density, and reduction of fine lines — PDRN stimulates endogenous collagen production.
• Dehydrated skin all seasons : the hyaluronic acid gradient deeply rehydrates, even under air conditioning or heating.
• Dull, tired complexions : glutathione and niacinamide revive radiance, gradually evening out skin tone.
• Post-treatment skin (peeling, microneedling, laser): PDRN accelerates healing and soothes inflammation — ideal during recovery phase.
• Fans of scientific protocols : if you’re already layering retinol, peptides, or vitamin C, this serum integrates without conflict (apply it before oils).

To avoid if : known allergy to fish-derived products (although PDRN is ultra-purified, protein traces may remain — patch test recommended on the forearm).

From the first application, the skin texture appears refined, and surface dehydration diminishes. After 2 weeks of daily use, the skin gains resilience — it "responds" better to touch, indicating that the collagen network is restructuring.

At 4 weeks, dehydration fine lines are visibly reduced, the complexion regains an even glow, and the skin barrier is less reactive to aggressors (pollution, cold). Anua consumer tests report a 24.64% improvement in deep hydration from the first use, and an 8.93% improvement in the instant plumping effect.

Use over 8 to 12 weeks: the texture is durably refined, elasticity improves (measurable with a cutometer), and the skin appears "rejuvenated" without injections — this is cellular regeneration in topical mode, accessible at home.

What is the difference between this serum and PDRN injections (like Rejuran)?

Injectables deposit PDRN directly into the dermis at high concentrations for deep and rapid regenerative effects. This topical serum uses an ultra-low molecular weight "smart capsule" encapsulation technology that enhances transdermal penetration, but the results are gradual and require daily application over several weeks. Less invasive, perfect for maintenance or as a post-injection complement.

Why does the serum have a natural emerald color?

The tint comes from the botanical extracts in the formula (Corallina Officinalis algae, Curcuma Longa) — no artificial dyes. This color disappears instantly upon application, leaving no trace on the skin or pillow.

Can I use this serum with retinol or vitamin C?

Yes, PDRN is compatible with all active ingredients. Apply it after your toner, before your active serums (retinol at night, vitamin C in the morning). It can even soothe retinol-related irritation thanks to its anti-inflammatory properties. Always finish with a cream and SPF during the day.

How long does a 30 ml bottle last with daily use?

About 2 to 3 months: 2-3 drops morning and evening are enough (or layered at night 3 times a week). The ultra-fluid texture spreads easily, no need to force the dose.

Is this serum suitable for oily or acne-prone skin?

Absolutely. The watery, non-greasy texture absorbs without leaving an occlusive film. Niacinamide regulates sebum, and PDRN helps repair post-inflammatory marks. Just avoid applying it on active open lesions.

Is this a vegan product?

No, PDRN (Sodium DNA) is derived from salmon sperm. If you’re looking for a vegan alternative, some brands offer synthetic PDRN or ginseng-derived PDRN, but this is not the case with this ANUA product.

Launched in South Korea, ANUA (a contraction of "Au Naturel") embodies minimalist K-beauty, focused on clean formulas, eco-designed packaging, and exemplary traceability. The brand became known for its Heartleaf (Houttuynia Cordata) range, ultra-soothing for sensitive skin, before diving into regenerative cosmetics with this PDRN Capsule 100 line.

The philosophy? To transpose Korean dermatological protocols — where injectable PDRN has been a standard since the 2000s — into accessible topical treatments, thanks to proprietary encapsulation technologies. ANUA works with laboratories specialized in marine biochemistry to guarantee the purity of PDRN (toxicity tests, absence of heavy metals) and formulates without synthetic fragrances or irritating essential oils.

All products are made in South Korea, dermatologically tested on sensitive skin, and contain no parabens, sulfates, or artificial colorants. Discover the entire ANUA range.

Full INCI: Water, Butylene Glycol, Propanediol, Glycerin, Hydrolyzed Hyaluronic Acid (29,049 ppm), 1,2-Hexanediol, Niacinamide, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Glutathione, Hydrolyzed Collagen, Sodium Hyaluronate (800 ppm), Coptis Japonica Root Extract, Adenosine, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Sodium DNA (100 ppm), Solanum Melongena (Eggplant) Fruit Extract, Hyaluronic Acid (30 ppm), Hydrolyzed Sodium Hyaluronate (30 ppm), Hydroxypropyltrimonium Hyaluronate (30 ppm), Potassium Hyaluronate (30 ppm), Sodium Hyaluronate Crosspolymer (30 ppm), Sodium Acetylated Hyaluronate (1 ppm), Ocimum Sanctum Leaf Extract, Citric Acid, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Sodium Citrate, Pentylene Glycol.

Key notes: Formula without synthetic fragrance, essential oils, or artificial colorants. The emerald color naturally comes from Corallina Officinalis algae extracts and turmeric. PDRN (Sodium DNA) is purified at high temperature to eliminate allergenic proteins — high biocompatibility, minimal risk of reaction.

The 11 forms of hyaluronic acid cover a full spectrum of molecular weights: acetylated and crosspolymer forms create a long-lasting hydrating film on the surface, while hydrolyzed (low molecular weight) forms penetrate deeply to plump the dermis. Anua’s "smart capsule" technology (ultra-low molecular weight liposomes) ensures controlled release of active ingredients without loss of efficacy.